Mental Health Startups funded by Y Combinator (YC) 2026

America is facing an addiction and mental health crisis. We're building a suite of AI agents to automate away the tasks that occupy half of the time and resources of behavioral health clinics—documentation, compliance, audits, and more. We save time, money, and mental bandwidth so that clinicians can stop chasing insurance reimbursements and go back to saving lives.

DraftTheRecord Desktop helps court reporters record and transcribe proceedings. Use the app to capture local recording sessions, create enhanced transcripts from audio/video, and review transcript content in a focused workspace designed for court reporting.

Personalized virtual clinical care is finally here for neurodegenerative diseases like Alzheimer's and related Dementias (Cognitive), Parkinson's and Huntington's (Movement), and ALS (Motor neuron). We provide a novel approach to care in these diseases, centering a patient and caregiver around a coordinator who quarterbacks patients through our full Multi-Disciplinary Care Resources to local aid, PT/OT and home health support. When you leave our clinic, it's not with a handful of paper referrals, but with our coordinators helping you book and find the best physicians, DME, trials, and even cheapest prescriptions. We are devoted to helping patients, from guidance on care and insurance to providing the full spectrum of investigational and clinical testing to improve outcomes. Synapticure was built by leading patient and caregiver advocates alongside leading clinicians, biotech executives and telemedicine executives to bring the neurodegenerative disease care and treatment experience into the 21st century, and is backed by the leading Venture funds and investors in the remote health and life sciences space.

Intellect is the global leader in hyperlocalised mental healthcare, serving 4 million lives across enterprise employers, insurers, healthcare systems, and governments in over 50 languages and 100 countries. With a comprehensive, AI-powered care ecosystem, Intellect seamlessly integrates digital therapeutics, virtual therapy, high-acuity crisis support, and specialty clinical treatment - delivered through its proprietary digital platforms and directly owned mental health clinics. Headquartered in Singapore with nine global offices, Intellect is backed by top investors including Tiger Global, Y Combinator, Insignia Ventures, and HOF Capital. It is trusted by hundreds of Fortune 500 companies and industry leading organisations.

We make it easy for anyone in India to access healthcare over Zoom, Meet, or WhatsApp. We provide care in 11 local languages. For every appointment, we provide a concierge who manages all logistics for the patient & handles the back-office work for doctors. With this, we have cracked the code to make telehealth work in India.

Legion Health is building autonomous medical care, starting with psychiatry. Our AI-native care-delivery platform currently automates 95% of the administrative work required for us to deliver direct patient care. We also became the first company ever to receive regulatory authorization to let AI prescribe psychiatric medications, allowing us to not only collapse health care’s admin costs but also its clinical labor costs—entirely shifting this industry’s economics from humans to tokens.

R.care is not just another diet program or calorie-counting app. It's a comprehensive, evidence-based solution designed to address the root causes of binge eating and provide lasting recovery. Say goodbye to waiting lists and hefty price tags, and take control of your relationship with food.

Gilgamesh is a pioneering, clinical stage mental health science-focused biotechnology company. We have a disciplined focus on developing innovative new chemical entities (NCEs) leveraging a unique combination of medicinal chemistry, intellectual property strategy, neuroscience & neurobiology, and drug development expertise. We are an experienced team, with proven success in biotech exits and inventions.

We help healthcare providers treat their gastrointestinal patients with AI-delivered therapy. Using machine learning and large language models, we learn from therapy data, outcomes, and physiology to deliver adaptive, scalable treatments for conditions like IBS - without the waitlist.

Luka is a software development company based in San Francisco, California. The company created Luka app, a new messenger with AI-powered chatbots. They help you find places to eat, do web search, make plans together, pick places to eat, play trivia games and lots of other things in a messenger. In 2016 Luka launched a closed testing of Replika, a new app that allows to create a personal AI friend that helps people deal with loneliness. The app is powered by a proprietary deep learning architecture.